< PreviousSCIENTIFIC PROGRAMME90 O0355Association of vitamin D with severity and outcome of COVID-19: clinical and experimental evidence E. Giamarellos-Bourboulis* (Athens, Greece), G. Renieris, G. Kassianidis, G. Damoraki, D.I. Droggiti, T. Gkavogianni, P. Koufargyris, K. Katrini OS090 11:00 - 12:00 Hall D 1-Hour Case Session Unusual fungal infections from around the globe ChairJoseph Meletiadis (Athens, Greece) O0356Adjunctive imiquimod for chromoblastomycosis: lending innate immunity a helping hand C. Logan* (London, United Kingdom), S. Krishna, N. Fox, M. Singh, K. Gordon, D. Macallan, T. Bicanic O0357Subcutaneous mycosesdue toEmergomyces pasteurianus: the first case report in Thailand L. Srikham* (Bangkok, Thailand), A. Chindamporn, R. Plongla O0358Invasive cerebral aspergillosis in non- neutropenic patients: a case series from western India D. Kumar* (Jodhpur, India), S. Samantaray, G.K. Bohra, V. Jain, S. Tiwari, D.S. Meena, N. Midha O0359Subcutaneous hyalohyphomycosis caused by Fusarium solani successfully treated with surgical removal in immunocompetent host M. Harnphadungkit* (Bangkok, Thailand), P. Phuensan O0360Mycobiome analysis reveals high fungal richness in lungs of acute respiratory distress syndrome after septic tank incident J. Kehrmann* (Essen, Germany), H.L. Verhasselt, M. Kudla, F. Herbstreit, S. Weidener, F. Reckinger, R. Scholtysik, J. Buer OF091 11:00 - 12:00 Hall K 1-Hour Mini-oral Flash Session New insights into pathogens virulence: human and microbial factors ChairsSusanne Haeussler (Braunschweig, Germany) Kimberly Kline (Singapore, Singapore) O0361Impact of peptidoglycan amidation on cell surface properties and biofilm formation in Staphylococcus aureus G. Cavaco* (Caparica, Portugal), B. Gonçalves, I. Grilo, H. De Lencastre, M. Miragaia, R. Sobral O0362CD6 deficiency impacts early immune response to bacterial sepsis C. Català* (Barcelona, Spain), M. Velasco-De Andrés, A. Leyton-Pereira, S. Casadó-Llombart, M. Martinez-Florensa, M. Saéz-Moya, R. Gutiérrez- Cózar, J. Garcia-Luna, F. Aranda, M. Consugra- Fernández, G. Mourglia-Ettlin, P. Engel, F. Lozano O0363Identification of novel small non-coding RNAs involved in biofilm and antibiotic resistance V. Pobre* (Oeiras, Portugal), B. Carvalho, C. Arraiano O0364Peptidoglycan recyclingenzymes AmpD and AnmK contribute to biofilm formation and twitching motility inA. baumannii A. Tajuelo* (Majadahonda, Spain), M. Lopez-Siles, M.C. Terrón, M. Sachse, D. Luque, M.J. Mcconnell O0365Biocides contribute to antibiotic resistance spread by increase functional eDNA release from biofilms O. Moshynets* (Kiev, Ukraine), T. Baranovskyi, O. Iungin, N. Kysil, L. Metelytsia, I. Pokholenko, V. Potochilova, G. Potters, K. Rudnieva, S. Rymar, I. Semenyuta, A. Spiers, O. Tarasyuk, S. Rogalsky O0366The acquisition of additional feedback loops optimises and speeds up the response of quorum sensing M. Fondi* (Florence, Italy), F. Di Patti, E. Perrin O0367Differential biofilm formation capacity and evolution in Candida glabrata clinical isolates: a genomics view I. Costa* (Lisbon, Portugal), P. Pais, M. Zolotareva, M. Cavalheiro, M. Galocha, R. Viana, M. Cacho Teixeira O0368Glycopeptidolipid(GPL) defects donot affect survival of rough Mycobacterium abscessus isolates on fomites and in chlorhexidine, as compared to their isogenic smooth counterparts M. Meir* (Haifa, Israel), D. Barkan O0369Catecholamine neurotransmitters are able to be used by Pseudomonas aeruginosa cells to access iron, a key nutrient I. Schalk* (Illkirch, France), Q. Perraud, S. Fritsch OF092 11:00 - 12:00 Hall L 1-Hour Mini-oral Flash Session Pathogenesis of fungal infections: the host and pathogen point of view ChairsElisa Borghi (Milan, Italy) Mihai Mares (Iasi, Romania) O0370Caenorhabditis elegans as a model for the study of dermatophyte infection and evaluation of 2-hydroxychalcone mediated by photodynamic therapy toxicity M.J.S. Mendes-Giannini* (Araraquara, Brazil), N.M.B. Bila, C.O.V. Vaso, L.R. De Assis, L.O. Regasini, C.R. Fontana, A.F.A. Ana Marisa, C.O. Caroline Barcelos O0371Myeloid immunity-driven gene expression profiling in bronchoalveolar lavage fluid of influenza- and COVID-19-associated pulmonary aspergillosis S. Feys* (Leuven, Belgium), C. Jacobs, L. Vanderbeke, L. Seldeslachts, M.R. Starick, K. Thevissen, Y. Debaveye, G. Hermans, P. Meersseman, K. Lagrou, A. Carvalho, J. Van Weyenbergh, J. Wauters Sunday, 24 April 2022FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 202391 O0372Candida albicans expresses an integrin-like adhesin that binds to the endothelium and triggers vascular disruption through a VE- cadherin signalling cascade D. Nader* (Dublin, Ireland), G. Curley, S. Kerrigan O0373Intestinal mycobiome compositional shifts and impaired Th17 signalling are associated with NAFLD severity N. Thielemann* (Würzburg, Germany), S. Leal Siliceo, R. Martin, M. Herz, M. Rau, H. Hermanns, A. Geier, G. Panagiotou, O. Kurzai O0374Microbial factors involved in the pathogenesis of vulvovaginal candidiasis: from carrier state to recurrent disease D. Shasha* (Tel Aviv, Israel), M. Elbaz, N. Mizrahi, A. Novikov, A. Lev-Sagie, R. Ben-Ami O0375Overcome double trouble: baloxavir marboxil suppresses influenza thereby mitigating secondary invasive pulmonary aspergillosis L. Seldeslachts* (Leuven, Belgium), C. Jacobs, B. Tielemans, E. Vanhoffelen, L. Van Der Sloten, S. Humblet-Baron, L. Naesens, K. Lagrou, E. Verbeken, J. Wauters, G. Vande Velde O0376Blockade of the PD-1/PD-L1 immune checkpoint pathway enhances host defense against Mucorales and improves outcomes in a murine model of invasive pulmonary mucormycosis S. Wurster* (Houston, United States), N.D. Albert, U. Bharadwaj, M.M. Kasembeli, D.P. Kontoyiannis O0377Unraveling host-pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella V. Garcia-Bustos* (Valencia, Spain), J. Peman, A.C. Ruiz-Gaitan, M.D. Cabanero-Navalon, A. Cabanilles-Boronat, L. Marcilla-Barreda, M. Fernandez-Calduch, I.A. Sigona-Giangreco, M. Salavert, M.Á. Tormo, A. Ruiz-Sauri O0378Gastrointestinal tract Candida spp. colonisation is mostly monoclonal: results derived from an intra-patient pilot study A. Mesquida* (Madrid, Spain), T. Vicente, P. Muñoz, J. Guinea, P. Escribano OF093 11:00 - 12:00 Hall M 1-Hour Mini-oral Flash Session COVID-19 vaccine immunogenicity and effectiveness in the immune compromised host ChairsMurat Akova (Ankara, Turkey) Marco Safadi (São Paulo, Brazil) O0379SARS-CoV-2 vaccine responses in patients with conditions leading to diminished immune capacity: the OCTAVE and OCTAVE-DUO trials T. De Silva* (Sheffield, United Kingdom) O0380Humoral and T cell specific immune responses to SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis using different disease- modifying therapies A. Aiello* (Rome, Italy), C. Tortorella, C. Gasperini, C. Agrati, C. Castilletti, S. Ruggieri, S. Meschi, G. Matusali, F. Colavita, C. Farroni, G. Cuzzi, E. Cimini, E. Tartaglia, V. Vanini, L. Prosperini, S. Haggiag, S. Galgani, M.E. Quartuccio, A. Salmi, F. Repele, A.M.G. Altera, F. Cristofanelli, A. D’abramo, N. Bevilacqua, A. Corpolongo, V. Puro, F. Vaia, M.R. Capobianchi, G. Ippolito, E. Nicastri, D. Goletti O0381Evaluation of the B and T cell response in patients with rheumatoid arthritis at one and six months following SARS-CoV-2 mRNA vaccination C. Farroni* (Rome, Italy), A. Picchianti-Diamanti, A. Aiello, B. Laganà, C. Agrati, C. Castilletti, S. Meschi, D. Lapa, S. Najafi Fard, G. Cuzzi, E. Cimini, G. Grassi, V. Vanini, A. Salmi, F. Repele, A.M.G. Altera, V. Puro, E. Nicastri, D. Goletti O0382Torquetenovirus viral load is predictive of SARS-CoV-2 vaccine response in lung transplant recipients F. Gallais* (Strasbourg, France), M. Solis, B. Renaud-Picard, A. Velay, M.J. Wendling, S. Caillard, R. Kessler, S. Fafi-Kremer O0383SARS-CoV-2 serological data and cellular response of patients withHIV during pre- and post-vaccination period in Tel Aviv Sourasky Medical Center T. Halperin* (Tel Aviv, Israel), L. Tau, D. Turner, A. Adler, R. Marom, S. Ahsanov, I. Levi, N. Matus, G. Gerber, S. Lev, T. Freund, D. Hagin O0384Analysis of post-vaccinal neutralising response against wild-type SARS-CoV-2 and Delta variant in haemodialysis patients and kidney recipients S. Alain* (Limoges, France), F. Lamarche, S. Hantz, C. Danthu, J.P. Rerolle, F. Toure O0385Comprehensive profiling of immune response to COVID-19 vaccination in patients with haematological malignancy B. Teh* (Melbourne, Australia), O. Nguyen, C. Lim, S. Tennakoon, N. Saunders, L. Rowntree, L. Allen, B. Chua, L. Kedzierski, L. Chee, M. Anderson, J. Seymour, M. Slavin, C. Tam, K. Kedzierska O0386Poor humoral immunogenicity to SARS-CoV-2 vaccination in people living with HIV (PLWH) with low CD4 count A. Antinori* (Rome, Italy), A. Cozzi-Lepri, A. Vergori, A. Tavelli, L. Marconi, S. Cicalini, A.M. Azzini, A. Sartor, A. Rodano’, S. Meschi, C. Agrati, F.M. Fusco, E. Righi, F. Abrizzani, G. Marchetti, E. Girardi, P. Viale, M. Giannella, E. Tacconelli, A. D’arminio Monforte Sunday, 24 April 2022SCIENTIFIC PROGRAMME92 O0387Response to SARS-CoV-2 vaccination in patients with antibody deficiency disorders C. Bracke-Manzanares* (Badalona, Spain), E. Ainsua-Enrich, N. Pedreño, M. Rodríguez De La Concepción, C. Ávila-Nieto, E. Pradenas, S. Marfil, R. Toledo, M. Font, C. Miranda, S. González, J. G. Prado, B. Mothe, C. Brander, N. Izquierdo- Useros, J. Vergara-Alert, J. Segalés, M. Massanella, R.M. Benítez, A. Romero, D. Molina-Morant, J. Blanco, B. Clotet, L. Mateu, J. Carrillo, M.L. Pedro- Botet OF09411:00 - 12:00 Hall O 1-Hour Mini-oral Flash Session New faces in the camp of AMR pathogens ChairsTBA Cecile Bebear (Bordeaux, France) O0387AAzithromycin resistanceinEscherichia coliandSalmonellafrom food-producing animals and meat in Europe M. Ivanova* (Kongens Lyngby, Denmark), A. Ovsepian, P. Leekitcharoenphon, A.M. Seyfarth, H. Mordhorst, S. Koeberl-Jelovcan, M. Milanov, G. Kompes, M. Liapi, T. Č erný, C. Thougaard Vester, A. Perrin-Guyomard, J. Hammerl, M. Grobbel, E. Valkanou, S. Jánosi, R. Slowey, P. Alba, V. Carfora, J. Avsejenko, A. Ceslova, A. Pereckiene, S. Sceponaviciene, D. Claude, R. Zerafa, K. Veldman, C. Boland, C. Garcia-Graells, P. Butaye, P. Wattiau, M. Zaj ą c, A. Ana, L. Clemente, M. Vaduva Angela, L.M. Romascu, N.M. Milita, A. Mojžišová, I. Zdovc, M.J. Zamora Escribano, C. De Frutos Escobar, K. Pedersen, G. Overesch, C. Teale, A.M.V. Brown, G.H. Loneragan, B. Guerra, P.A. Beloeil, R.S. Hendriksen, J.S. Kjeldgaard, V. Bortolaia O0388Legionella pneumophila antibiotic resistance: from myth to reality S. Jarraud* (Lyon, France), C. Ginevra, L. Beraud, H. Bentayeb, C. Allam, J. Chastang, M. Ibranosyan, V. Decroix, G. Descours O0389Antibiotic resistance prevalence in Helicobacter pylori in gastric biopsies A. Bellés-Bellés* (Lleida, Spain), S. Mormeneo Bayo, D. Bayas Pastor, R. Monclus Millanes, S. Chordi Barrufet, M.L. Cruellas Tremps, A. Jover Saenz, M. Planella De Rubinat, M. Garcia Gonzalez O0390Antimicrobial susceptibility testing: the intriguing scenario in anerobes clinical isolates M. Casarotto* (Verona, Italy), M. Tartaglia, D. Gibellini, A. Mazzariol O0391National survey of antimicrobial resistance amongst clinical Bacteroides and Prevotella isolates in The Netherlands K. Boiten* (Groningen, Netherlands), D. Notermans, R. Rentenaar, J. Van Prehn, L. Bode, I. Maat, W. Van Der Zwet, N. Arents, T. Siebers, S. De Greeff, A. Hendrickx, E. Kuijper, L. Veloo O0392Genome analysis of macrolide-resistant Haemophilus influenzaeandHaemophilus parainfluenzaestrains isolated at Bellvitge University Hospital I. Cadenas Jiménez* (Barcelona, Spain), A. Carrera Salinas, A. González Díaz, L. Saiz Escobedo, D.A. Vázquez Sánchez, S. Calvo Silveria, D. Berbel, F. Tubau, C. Ardanuy, S. Martí O0393Alarming increase in antimicrobial resistance in Helicobacter pylori in the Netherlands, 2010- 2019 S. Woudt* (Bilthoven, Netherlands), R. Veenendaal, A. Schoffelen, E. Kuijper O0394Antibiotic resistance in Haemophilus influenzae isolates obtained from patients at outpatient departments in Germany, 2019/2020 H. Claus* (Würzburg, Germany), T.T. Lâm, E. Wohlfarth, U. Vogel, M. Kresken O0395Population structure of carbapenemase- producing Morganella spp. R. Bonnin* (Le Kremlin-Bicetre, France), E. Creton, A. Perrin, D. Girlich, A.B. Jousset, C. Emeraud, K. Hopkins, P. Bogaerts, N. Pfennigwerth, M. Gniadkowski, A. Hendrickx, K. Van Der Zwaluw, P. Apfalter, R. Hartl, V. Heringova, J. Hrabak, G. Larrouy-Maumus, E. Rocha, T. Naas, L. Dortet FO095 12:15 - 13:15 Arena 1 Open Forum Is Twitter the new ID textbook? ChairJose Ramon Pano-Pardo (Zaragoza, Spain) F0396RIP my mentions: science by social media in the age of disinformation Angela Rasmussen (Saskatoon, Canada) F0397Is social media worth my time? Carlos Del Rio (Atlanta, United States) F0398#IDTwitter: infectious diseases medicine in the age of social media Stone Neil (London, United Kingdom) F0399Bugs, drugs, and social media: Twitter as a tool for advancing the field of infectious diseases Timothy Gauthier (Miami, United States) FO095A 12:15 - 13:15 Arena 2 Open Forum When science gets politicised; experiences from the COVID-19 pandemic ChairInes Steffens (Solna, Sweden) F0399AIn the eye of the public: politicised science, the epidemiologists experience TBA F0399BIn the eye of the public: politicised science, the microbiologists experience Marion Koopmans (Rotterdam, Netherlands) Co-organised with: European Centre for Disease Prevention and Control (ECDC) Sunday, 24 April 2022ECCMID Open Forum 2022 Sunday 24 April 2022 12:15 – 13:15 WEST Arena 1 OPEN FORUM 2022 1-Hour Open Forum Chair:Jose Ramon Paño-Pardo, Zaragoza, Spain RIP my mentions: science by social media in the age of disinformation Angela Rasmussen, Saskatoon, Canada Is social media worth my time? Carlos del Rio, Atlanta, United States #IDTwitter: infectious diseases medicine in the age of social media Neil Stone, London, United Kingdom Bugs, drugs, and social media: Twitter as a tool foradvancingthefieldofinfectiousdiseases Timothy Gauthier, Miami, United States Is Twitter the new ID textbook?SCIENTIFIC PROGRAMME94 IC KN09613:30 - 14:30Hall A Keynote scientific interview Never let an outbreak go to waste: how COVID-19 has changed hospital epidemiology and infection prevention and control Interviewer Mary Horgan (Cork, Ireland) K040013:30 Alison Helen Holmes (Berlin, Germany) Alison Holmes is the Professor of Infectious Diseases and the Director of the NIHR Health Protection Research Unit in Healthcare Associated Infections and AMR and the Centre for Antimicrobial Optimisation (CAMO), at Imperial College London. She is also the current President of the International Society for Infectious Diseases. Prof. Holmes is an NIHR Senior Investigator and has a longstanding career in the NHS. She serves on WHO Expert groups related to antimicrobial use, AMR, infection prevention, sepsis, and COVID-19. She leads a large international, multidisciplinary infectious disease research programme, including collaborative programmes funded by NIHR, ESRC, UKRI and Wellcome Trust on the improved management and prevention of infections, particularly focusing on the optimising of antimicrobial use and addressing antimicrobial resistance through the integration of social sciences, the application of innovative approaches and technologies and the development of precision medicine. Co-organised with: European Committee on Infection Control (EUCIC) Steering Committee Fireplace Session24 April, 15:00 - 16:00 CM SY097 13:30 - 15:30 Hall B Symposium Impact of rapid diagnostics for community-acquired acute respiratory tract infections (CA-ARTI) on antibiotic stewardship ChairsMaurizio Sanguinetti (Rome, Italy) TBA S040113:30What is diagnostic stewardship and why should we care? Bhanu Sinha (Groningen, Netherlands) S040214:00Consensus about the use of rapid diagnostics for the management of CA-ARTI Eva Polverino (Barcelona, Spain) S040314:30Point-of-care testing and antibiotic prescribing for CA-ARTI in primary care during the COVID-19 pandemic Alike Van Der Velden (Utrecht, Netherlands) S040415:00Rapid diagnosis of CA-ARTI in the ambulatory care or in the emergency room: are there differences? Cristina Prat Aymerich (Utrecht, Netherlands) Co-organised with: VALUE-Dx, European Respiratory Society (ERS) PH SY098 13:30 - 15:30 Hall E Symposium Vaccinated or non-vaccinated: patients are not healthcare workers, and the flu is not COVID-19 ChairsWalter Zingg (Zurich, Switzerland) Nasia Safdar (Madison, United States) S040513:30How vaccines help healthcare workers to stay safe Martin Kiernan (Ormskirk, United Kingdom) S040614:00COVID-19 vaccine revisited: how to handle unvaccinated, poorly vaccinated or immunosuppressed patients Hilary Humphreys (Dublin, Ireland) S040714:30The triangle of personal protective equipment, vaccination and screening make our hospitals safe Nico Tom Mutters (Bonn, Germany) S040815:00Protecting the immunocompromised healthcare worker Gabriel Birgand (Nantes, France) Co-organised with: EUCIC Steering Committee ID SY099 13:30 - 14:30 Hall I Symposium The changing epidemiology of West Nile fever virus in Europe ChairsTamas Bakonyi (Solna, Sweden) TBA S040913:30Epidemiological trends West Nile virus in Western Europe Chantal B.E.M. Reusken (Bilthoven, Netherlands) S041014:00The causes and consequences of increasing West Nile virus activity in Europe Eleni Patsoula (Athens, Greece) Co-organised with: ESCMID Study Group for Public Health Microbiology (ESGPHM) Sunday, 24 April 2022FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 202395 ID EW100 13:30 - 15:30 Hall C Educational Workshop Subacute and chronic meningitis ChairsMatthijs Brouwer (Amsterdam, Netherlands) Emma Cecilia Wall (London, United Kingdom) W041113:30Infectious causes of chronic meningitis: diagnostic considerations and workup Bettina Pfausler (Innsbruck, Austria) W041214:00Non-infectious differential diagnosis in patients with subacute and chronic meningitis Uta Meyding-Lamadé (Frankfurt, Germany) W041314:30Post-Lyme disease syndrome: what is it and how to deal with it? Randi Eikeland (Kristiansand, Norway) Co-organised with: The Collaborative on Fatigue Following Infection (COFFI), ESCMID Study Group for Infectious Diseases of the Brain (ESGIB) CM EW101 13:30 - 15:30 Hall F Educational Workshop Don’t get lost in translation: the use of preclinical PK/PD models in anti-infective drug development ChairsCornelia Landersdorfer (Parkville, Australia) Markus Zeitlinger (Vienna, Austria) W041413:30The role of in vitro models Alasdair P. MacGowan (Bristol, United Kingdom) W041514:00The role of in vivo models William Couet (Poitiers, France) W041615:00The role of in silico models Elisabet Nielsen (Uppsala, Sweden) Co-organised with: ESCMID PK/PD of Anti- Infectives Study Group (EPASG) PH EW102 13:30 - 15:30 Hall G Educational Workshop How to use intervention and implementation research to mitigate AMR ChairsBruno Gonzalez-Zorn (Madrid, Spain) Nandini Sreenivasan (Copenhagen, Denmark) W041713:30Intervention, operational and implementation research: key constructs Sabiha Essack (Durban, South Africa) W041814:00Developing an implementation research roadmap Raheelah Ahmad (London, United Kingdom), Alexandre Rabello Tenorio Da Costa (New York, United States) Co-organised with: International Centre for Antimicrobial Resistance Solutions (ICARS) OS103 13:30 - 15:30 Hall M 2-Hour Oral Session The Public Health response to COVID-19 ChairsDebby Bogaert (Edinburgh, United Kingdom) David Fisman (Toronto, Canada) O0419Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission D. Aggarwal* (Cambridge, United Kingdom), A.J. Page, U. Schaefer, G.M. Savva, R. Myers, E. Volz, N. Ellaby, S. Platt, N. Groves, E. Gallaghar, N.M. Tumelty, T. Le-Viet, G.J. Hughes, C. Chen, C. Turner, S. Logan, A. Harrison, S.J. Peacock, M. Chand, E.M. Harrison O0420Lockdown impact on mixing patterns and behaviour relevant to the spread of infection in France during the COVID-19 pandemic R. Millot* (Poitiers, France), L. Opatowski, P. Beutels, N. Hens, B. Dervaux, G. Beraud O0421Impact of COVID-19 nationwide lockdowns on emergency hospitalisations due to chronic lower respiratory diseases: a national interrupted time series analysis for Ireland S. O’ Regan* (Dublin, Ireland), A. Mc Greal-Bellone, J. O’ Connell, P. Carey, A. Heeney, J. Harte, O. Donnelly, K. Bennett, E. De Barra O0422Fake news or credible source? Assessing the quality of online resources informing the public about COVID-19 in two countries C. Turnbull* (London, United Kingdom), J.K. Tan, L. Yamanouchi, J.Y. Tan, R. Som O0423Differences in diagnostic cycle threshold values of SARS-CoV-2 genes: a novel epidemiological tool to monitor variant prevalence A.E. Bordoy* (Barcelona, Spain), V. Saludes, D. Panisello, G. Clarà, A. París, C. Casañ, M. Guerrero-Murillo, B. Rodríguez-Ponga, M. Noguera-Julian, F. Català-Moll, P. Armengol, M. Casadellà, M. Parera, L. Sumoy, B. Clotet, M. Giménez, I. Blanco, E. Martró, P.J. Cardona O0424Estimation of the impact of hospital-onset SARS-CoV-2 infections on length of stay in English hospitals using causal inference J. Stimson* (London, United Kingdom), K. Pouwels, R. Hope, B. Cooper, A. Presanis, J. Robotham O0425Identifying targets for testing by machine learning Y. Asai* (Tokyo, Japan), S. Tsuzuki O0426Despite the level of uncontrolled spread of COVID-19 in Brazil, the country of soccer, can entire seasons of professional players be carried out safely? Yes, we did! C. Starling* (Belo Horizonte, Brazil), J. Pagura, A.D.C. Clovis, N. Roberto, W. Sergio, P. André, C. Sergio, P. Andreia, F. Sérgio, G. André, T. Edilson, C. Braulio Sunday, 24 April 2022SCIENTIFIC PROGRAMME96 O0427Antimicrobials use estimation in 2020 from the SARIMA model in Japan A. Ono* (Tokyo, Japan), R. Koizumi, S. Tsuzuki, Y. Asai, M. Ishikane, Y. Kusama, N. Ohmagari O0428Impact of long-COVID on health-related quality of life in Japanese COVID-19 patients S. Tsuzuki* (Antwerp, Belgium), Y. Miyazato, M. Terada, S. Morioka, N. Ohmagari, B. Philippe OS104 13:30 - 14:30 Hall D 1-Hour Case Session Challenging mycobacterial infections ChairDelane Shingadia (London, United Kingdom) O0429Tuberculosis meningitis: a 30-year review F. Sánchez-Martínez* (Barcelona, Spain), M.D.M. Arenas-Miras, S. Castañeda-Espinosa, N. Jové-Caballé, E. Carrió-Díez, H. Knobel, J.P. Horcajada O0430Mycobacterium haemophilum in Singapore: a multi-centre descriptive case series J. Sim* (Singapore, Singapore), C.M.D. Lai, E.P. Conceicao, J.X.J. Soh, T.T. Tan, C.C. Ang, C.F. Yung, S.T. Thio, B.K.W. Yeo, J.Y. Pan, S.X. Lee, S.Y. Tan, S. Sadarangani, L.H. Sng O0431Nosocomial transmission of Mycobacterium abscessus in patients with COVID-19 admitted to an intensive care unit in Madrid A. Estévez* (Madrid, Spain), V. Sampériz, M.J. Ruiz Serrano, M. Marín, M. Sancho, B. Moreno, A. Garrido, C. Mata, L. Perez-Lago, D. García De Viedma, B. Padilla, P. Muñoz O0432Cutaneous tuberculosis verrucosa cutis presenting as a fungating mass on the foot: a case report A. Uy* (Quezon City, Philippines), A. Masbang O0433Clinical description, antimicrobial resistance, and treatment outcomes for patients with invasive Mycobacterium chelonae infection from one UK hospital: a 15-year retrospective case series J. Meiring* (Sheffield, United Kingdom), A. Temple, S. Francis, H. Kaur, J. Snowden, D. Partridge OF105 13:30 - 14:30 Hall H 1-Hour Mini-oral Flash Session Epidemiology of parasites, here and there ChairsAnna Checkley (London, United Kingdom) Florence Robert-Gangneux (Rennes, France) O0433AParasites (Blastocystis hominis, Dientamoeba fragilis, Cryptosporidiumspp., Cyclospora cayetanensis, Entamoeba histolytica, Giardia lamblia) laboratory diagnostic in Latvia 2019-2021 K. Ventins* (Riga, Latvia), O. Savicka, T. Bogurdovica, S. Nikisins O0433BA machine learning model for evaluating strongyloidiasis screening strategies in immigrant populations A. Rodríguez-Guardado* (Oviedo, Spain), A. García- Pérez, J. Fernández-Martínez, J. Boga, E. De Andrés, L. Casado, J. Fernández, F. Vázquez, M. Rodríguez-Pérez O0433CMonitoring soil-transmitted helminth infections in treated and non-treated individuals over three years of community-wide mass drug administration within the Geshiyaro project in Ethiopia S. Santiago* (London, United Kingdom), R. Maddren, L. Toby, K. Suprabhath, F. Ewnetu, C. Melkie, M. Hussein, W. Yonas, T. James, P. Anna, O. Alison, F. Kathryn, A. Ufaysa, M. Birhan, M. Zelalem, T. Geremew, S. Mihretab, R. Roy O0434Occurrence ofGiardia duodenalis and Cryptosporidiumspecies, not-related to travel, in a country generally with a high hygienic standard G.N. Hartmeyer* (Odense, Denmark) O0435Higher than expected incidence of leishmaniasis in the city of Madrid (Spain): possible relationship to a close outbreak focus J. Alonso-Carrillo* (Madrid, Spain), S. Castaño, M. Prieto, N. Valdeolivas, A. López-Alba, M. Fernández-Ruiz, R. San Juan, M. Lizasoain, A. Pérez De Ayala, J.M. Aguado, F. López-Medrano O0436The first detection of Leishmania infantum parasite in Forcipomyia species L. Remadi* (Monastir, Tunisia), H. Baba, D. Slama, D. Farjallah, H. Babba, N. Haouas O0437Genomic epidemiology ofCryptosporidium parvumin Europe G. Bellinzona* (Pavia, Italy), T. Nardi, M. Castelli, T. Autio, Y. Blanchard, R.M. Chalmers, R. Davidson, A. De Jong, T. Embom, J. Gomes, G. Karadjian, C. Klotz, P. Jokelainen, E. Östlund, J. Plutzer, L.J. Robertson, G. Robinson, A.R. Sannella, J. Sroka, C. Rune Stensvold, K. Troell, P. Vatta, D. Sassera, S.M. Cacciò O0438Endemic lizards Gallotia gallotiinfected by invasive nematode Angiostrongylus cantonensis in Tenerife, Spain E. Izquierdo-Rodriguez* (La Laguna, Spain), L. Anettová, P. Foronda, D. Modrý O0439Pilot survey of cystic echinococcosis in Masaai livestock-keeping communities of northern Tanzania F. Tamarozzi* (Negrar Di Valpolicella, Italy), T. Kibona, W. De Glanville, T. Mappi, E. Adonikamu, A. Salewi, K. Misso, V. Maro, A. Casulli, A. Santoro, F. Santolamazza, B. Mmbaga, C. Sarah Sunday, 24 April 2022FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 202397 Sunday, 24 April 2022 OF106 13:30 - 14:30 Hall K 1-Hour Mini-oral Flash Session All about intracellular and rare bacteria ChairsMatilda Berkell (Antwerpen, Belgium) Gilbert Greub (Mollie-Margot, Switzerland) O0440“When old drugs learn new tricks”: drug repurposing of thioridazine to treat Salmonella infections D. Alves Ferreira* (Dublin, Ireland), C. Roma Rodrigues, P.V. Baptista, A. Fernandes, M. Martins O0441Identification of Streptomyces spp. in a clinical sample: always a contamination? Results of a French national retrospective study E. Gras* (Paris, France), E. Bergeron, M. Puges, M. Ducours, C. Leleux, L. Amoureux, B. Jean, I. Bendjelloul, F. Camelena, R. Chenouard, R. Mahieu, A. Toro, A. Lecoustumier, O. Lortholary, O. Lemenand, V. Rodriguez-Nava, D. Lebeaux O0442The retropepsin-type protease APRc as a novel Ig-binding protein and moonlighting immune evasion factor of Rickettsia I. Simões* (Coimbra, Portugal), P. Curto, A. Barro, C. Almeida, R.S. Vieira-Pires O0443Characterisation of truncated internalin A in Listeria monocytogenes clinical isolates within the surveillance of invasive listeriosis in Lombardy region, northern Italy M. Gori* (Milan, Italy), C. Fappani, S. Piazza, G. Magagna, E. Spinelli, S. Bianchi, D. Colzani, G. Finazzi, A. Amendola, E. Tanzi O0444Fluorescence in situ hybridisation for detecting Coxiella burnetii in tissue samples: not as golden as we hoped J.M. Weehuizen* (Utrecht, Netherlands), S.B. Buijs, T.K. Jensen, A.I.M. Hoepelman, C.P. Bleeker-Rovers, P.C. Wever O0445Next-generation sequencing of historic and contemporary strains of Fusobacterium necrophorum at the UK anaerobe reference unit: what does it reveal? M. Perry* (Cardiff, United Kingdom), K. Vranckx, T. Morris O0446Burden of Lyme disease (BOLD) study: a prospective active surveillance study in European endemic regions, interim results A. Loew-Baselli* (Vienna, Austria), A. Pilz, J. Stark, L.R. Harper, J.S. Berglund, V. Cibik, J. Weimer, A. Moniuszko-Malinowska, L. Dybova, D. Zakova, B. Parslow, J. Edwards, K. Chauhan, S. Valluri, L. Jodar, B. Gessner, B. Elizabeth O0447Implementation of Campylobacter laboratory surveillance using whole genome sequencing in the Netherlands M. Van Den Beld* (Bilthoven, Netherlands), R. Pijnacker, O.E. Van Den Berg, K. Van Der Zwaluw, A. Hernandez Segura, E. Franz, T. Bosch O0448Invasive Aggregatibacter species infections in a London teaching hospital over a 4-year period: a case series of 27 patients A. Bapat* (London, United Kingdom), O. Lucey, M. Eckersley, S. Ranasinghe, J. Lambourne KN10714:45 - 15:45Hall A Keynote lecture AI revolution in medicine Chairs Adrian Egli (Basel, Switzerland) Vitali Sintchenko (Sydney, Australia) K044914:45 Suchi Saria (Baltimore, United States) Suchi Saria, PhD, is the Founder and CEO of Bayesian Health, the John C. Malone endowed chair and Associate Professor of Computer Science, Statistics and Health Policy, and the Director of the Machine Learning, AI and Healthcare Lab at Johns Hopkins University. Her research has pioneered the development of next generation diagnostic and treatment planning tools that use statistical machine learning methods to individualize care. She has written several of the seminal papersinthefieldofMLanditsuseforimprovingpatient care and has given over 250 invited keynotes and talks to organizations including the NAM, NAS, and NIH. Dr. Saria has served as an advisor to several Fortune 500 companies and her work has been funded by leading organizations including the NIH, FDA, NSF, DARPA and CDC. At Bayesian Health, Dr. Saria is operationalizing her decades ofresearchinthefieldtomakehealthcareproactiveby empowering physicians, nurses, and care team members with real-time data to save lives. Dr. Saria has been featured in Bloomberg News and PBS NOVA and she has won several awards for excellence in AI and care delivery, including IEEE’s “AI’s 10 to Watch”, Sloan Fellow, MIT Tech Review’s “35 Under 35”, National Academy of Medicine’s list of “Emerging Leaders in Health and Medicine”, DARPA’s List of Rising Stars, World Economic Forum’s 100 Brilliant Minds Under 40, Rock Health’s “Top 50 in Digital Health”, The Armstrong Award for Excellence in Quality and Safety; Node. Health’s Best in Class Digital Health Intervention Award; and Society of Critical Care Medicine’s AnnualScientificAward. Fireplace Session24 April, 16:00 - 17:00 PH SY108 14:45 - 15:45 Hall H Symposium Imported cutaneous leishmaniasis in Europe by the thousand: is it all the same? ChairsSara Karlsson Sobirk (Lund, Sweden) Kristine Morch (Bergen, Norway) S045014:45Imported cutaneous leishmaniasis in migrants Özgür Kurt (Istanbul, Turkey) S045115:15Cutaneous leishmaniasis in South America Dalila Martinez (Lima, Peru) Co-organised with: ESCMID Study Group for Clinical Parasitology (ESGCP)SCIENTIFIC PROGRAMME98 Sunday, 24 April 2022 ID SY109 14:45 - 15:45 Hall J Symposium The changing picture of childhood pneumonia ChairsDavid Goldblatt (London, United Kingdom) Catherine Satzke (Melbourne, Australia) S045214:45Impact of COVID-19 pandemic on epidemiology of childhood pneumonia Shabir Madhi (Randburg, South Africa) S045315:15Impact of the pandemic on childhood vaccination globally Kate O’Brien (Geneva, Switzerland) OS110 14:45 - 15:45 Hall I 1-Hour Oral Session Elimination of HBV and HCV ChairsArjan Harxhi (Tirana, Albania) Dorota Zar ę bska-Michaluk (Kielce, Poland) O0454Reduction of the occurrence of occult HBV infection in infants by increasing the dose of hepatitis B vaccine: a large prospective cohort study L. Yi* (Beijing, China), X. Yingchun O0455ScanVir: a new concept towards the end of hepatitis C in 2025 in France M.L. Debette-Gratien* (Limoges, France), S. Alain, S. François, C. Rigaud, P. Carrier, C. Chevalier, B. Abraham, A.L. Burgevin, B. Denenes, L. Courat, J. Zattoni-Leroy, E. Caux-Nussbaum, P. Nubukpo, V. Loustaud-Ratti O0456Impact of the COVID-19 pandemic on treatment access and follow-up of viral hepatitis patients N. Baykam* (Çorum, Turkey), F. Eser, R. Güner, Y. Gürbüz, M. Akdo ğ an, Z. Bilgiç, N. Korkmaz, D. Arı, G. Ş anlıda ğ , Ş . Kesim Uçar, T. Düzenli, T. Yamazhan O0457HCV micro-elimination in the hospital setting: the results of the HCV-free Caserta hospital project M. Pisaturo* (Naples, Italy), V. Messina, L. Alessio, A. Russo, N. Coppola O0458Impact of the COVID-19 epidemic on reported chronic hepatitis C in the Netherlands, 2019- 2021 E. Den Boogert* (Bilthoven, Netherlands), P. Zantkuijl, I.K. Veldhuijzen, E. Op De Coul OS111 14:45 - 15:45 Hall D 1-Hour Case Session Management of orthopaedic infections ChairMarjan Wouthuyzen-Bakker (Groningen, Netherlands) O0459Bacteriophage therapy: clinical experience in the management of eight patients withdifficult-to- treat infections P. Morovic* (Berlin, Germany), L. Ponce Benavente, T. Tkilaishvili, D. Margaryan, S. Karbysheva, P. Carsten, A. Trampuz O0460Tropheryma whipplei spondylodiscitis: case report A. Ferrari* (Padua, Italy), S. Lo Menzo, S. Gardin, F. Raumer, M. Trevenzoli, A. Cattelan O0461First Italian case of successful personalised phage therapy in addition to antibiotic in the treatment of chronic hip prosthesis infection caused by Pseudomonas aeruginosa N. Cesta* (Rome, Italy), M. Pini, T. Mulas, E. Ippolito, J. Wagemans, L. Sarmati, R. Lavigne, A. Tavanti, M. Andreoni, M. Di Luca O0462Persistent Brucella Melitensisbacteraemia due to bilateral prosthetic knee infection: a case report C. Aldieri* (Cuneo, Italy), E. Borgogno, E. Monge, F. Sordella, R. Curetti, V. Del Bono O0463A rare case of periprosthetic streptobacillosis: rapid identification via nanopore sequencing after inconclusive VITEK MS results R. Spott* (Jena, Germany), B. Schleenvoigt, B. Edel, M.W. Pletz, C. Brandt OF112 14:45 - 15:45 Hall K 1-Hour Mini-oral Flash Session Update on epidemiology and resistance in Staphylococcus aureus and Enterococcus ChairsSören G. Gatermann (Bochum, Germany) Margreet C. Vos (Rotterdam, Netherlands) O0464Antimicrobial resistance and genetic diversity of Enterococcus and Staphylococcus isolates from wastewater and environmental water samples from two South African provinces J. Makumbi* (Pretoria, South Africa), M. Kock, S. Ogundare, A. Smith, G. Van Der Zel, M. Ehlers O0465Staphylococcus aureus carriage variation in the nasotracheal cavities of storks from southern Spain, with a focus on the MSSA-CC398 clone I.N. Abdullahi* (Logroño, Spain), G. Juárez- Fernández, D. Mínguez-Romero, P. Eguizábal, R. Fernández-Fernández, U. Hoffle, M. Zarazaga, C. Lozano, C. Torres O0466Emergence of staphylococcal non-wild-type populations to biocides in a One Health perspective: are there reasons for concern? S.S. Costa* (Lisbon, Portugal), C. Ferreira, C. Morais, P. Abrantes, C. Pomba, I. Couto O0467Vancomycin-resistant Enterococcus faecium causing hospital infections in Porto, Portugal (2009-2020): a retrospective analysis A.C. Almeida-Santos* (Porto, Portugal), B. Duarte, A.P. Pereira, M. Cabral, L.M. Silva, H. Ramos, A. Read, V. Alves, C. Novais, A.R. Freitas, L. Peixe O0468Prevalence of pvl-positive methicillin-resistant Staphylococcus aureus (MRSA) isolated from imported, farmed fish at retail in Germany S. Maurischat* (Berlin, Germany), S. Schaarschmidt, T. Lienen, M. Grobbel, B.A. Tenhagen, K. AltFINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 202399 Sunday, 24 April 2022 O0469Transmission of methicillin-susceptible Staphylococcus aureus among healthcare workers, patients and the environment in a large acute hospital with a history of endemic methicillin-resistant Staphylococcus aureus (MRSA) under non-outbreak conditions investigated using whole genome sequencing P. Kinnevey* (Dublin, Ireland), A. Kearney, M. Earls, T. Poovelikunnel, G. Brennan, A. Shore, H. Humphreys, D. Coleman O0470Fine-typing of the endemic vancomycin- resistant Enterococcus faecium ST117 clone from Germany K. Xanthopoulou* (Cologne, Germany), F. Dyrkell, D. Arnellos, F.B.A.G. Erre, H. Seifert, P.G. Higgins O0471Genomic epidemiology and characterisation of penicillin-sensitive MSSA isolates from invasive bloodstream infections in China: an increasing prevalence and higher diversity in genetic typing be revealed W. Zhou* (Hangzhou, China), Y. Jin, Y. Xiao O0472Linezolid-resistant VRE (Enterococcus faecium) from hospital patients in Germany, 2016-2020 G. Werner* (Wernigerode, Germany), C. Fleige, R. Weber, M. Fischer, J. Bender VW113 14:45 - 15:45 Arena 2 Virtual Walk Through Efficacy and immunity of established vaccines ModeratorJoanna Maria Zajkowska (Bialystok, Poland) ReviewerMichael Dalager-Pedersen (Aalborg, Denmark) SY114 16:15 - 18:15 Hall A Symposium Late-breaking research from The Lancet group ChairsEmma Grainger (London, United Kingdom) Zoe Mullan (London, United Kingdom) Details on the selected publications will be availble at a later stage ID SY115 16:15 - 18:15 Hall B Symposium Updates on HIV treatment and prevention ChairsJose Arribas (Madrid, Spain) Georg Behrens (Hannover, Germany) S047316:15Progress toward reaching HIV prevention and treatment targets in Europe Teymur Noori (Solna, Sweden) S047416:45HIV treatment: which are the drugs? Marta Vasylyev (Lviv, Ukraine) S047517:15HIV and the cure: what is new in the HIV the vaccine research? Simona Ruta (Bucharest, Romania) S047617:45Patients perspectives on PrEP Tamás Bereczky (Berlin, Germany) Co-organised with: European AIDS Clinical Society (EACS) CM SY116 16:15 - 18:15 Hall E Symposium Host and viral factors in COVID-19, what makes us sick? ChairsMario Ramirez (Lisbon, Portugal) Annelies Verbon (Utrecht, Netherlands) S047716:15Host factors for disease severity of COVID-19 Qian Zhang (New York, United States) S047816:45The interplay between host and viral factors in the evolving COVID-19 pandemic Marion Koopmans (Rotterdam, Netherlands) S047917:15Studying T-cell response after vaccination in COVID-19 transplant recipients Coretta Van Leer Buter (Groningen, Netherlands) S048017:45Genetic variants in the human population driving severe COVID Alessandra Renieri (Siena, Italy) Co-organised with: UEMS Section of Medical Microbiology, UEMS Section of Infectious Diseases, ESCMID Study Group for Infections in the Elderly (ESGIE) ID SY117 16:15 - 18:15 Hall F Symposium Emerging priorities and developments for antifungals and fungal infections ChairsAna Alastruey-Izquierdo (Madrid, Spain) Arnaldo Colombo (São Paulo, Brazil) S048116:15Where do novel antifungals fit in clinical practice? Nina Khanna (Basel, Switzerland) S048216:45New fungal diagnostic tests to support the use of novel antifungal agents Luis Ostrosky-Zeichner (Houston, United States) S048317:15WHO Fungal Priority Pathogens List for research and development Hatim Sati (Geneva, Switzerland) S048417:45Challenges in clinical management of invasive fungal infections in low- and middle-income countries Arunaloke Chakrabarti (Chandigarh, India) Co-organised with: International Immunocompromised Host Society (ICHS), World Health Organization (WHO)Next >