< PreviousSCIENTIFIC PROGRAMME100 ID EW118 16:15 - 18:15 Hall I Educational Workshop The different faces of Lyme borreliosis ChairsAnna J. Henningsson (Jönköping, Sweden) Mateusz Markowicz (Vienna, Austria) W048516:15In the skin: dermatologic manifestations of Lyme borreliosis Franc Strle (Ljubljana, Slovenia) W048616:45In the brain: Lyme neuroborreliosis Randi Eikeland (Kristiansand, Norway) W048717:45In the joints: Lyme arthritis Benoît Jaulhac (Strasbourg, France) Co-organised with: ESCMID Study Group for Lyme Borreliosis (ESGBOR) ID EW119 16:15 - 18:15 Hall J Educational Workshop How to make clinical trials more efficient ChairsMarc J.M. Bonten (Utrecht, Netherlands) Herman Goossens (Edegem, Belgium) W048816:15Which operational factors determine the efficiency of clinical trial execution Marouan Zarrouk (Wuppertal, Germany) W048916:45Which design aspects can enhance clinical trial efficiency Marlieke E.A. De Kraker (Geneva, Switzerland) W049017:45What is an adaptive platform trial Cornelis H. Van Werkhoven (Utrecht, Netherlands) Co-organised with: European Clinical Research Alliance on Infectious Diseases (ECRAID) OS120 16:15 - 18:15 Hall C 2-Hour Oral Session Sepsis biomarkers: from gene to score ChairsPierre-Yves Bochud (Lausanne, Switzerland) Fanny Lanternier (Paris, France) O0491Is invasive pneumococcal disease a marker of an underlying primary immunodeficiency? A. Gwee* (Melbourne, Australia), L.K. Phuong, A. Cheung, T. Cole, R. Agrawal, C. Butters, J. Clark, N. Curtis, A. Daley, H. Dobinson, C. Frith, N.S. Hameed, H. Hernstadt, P. Loke, S. Ojaimi, B. Mcmullan, E.G. Sharp, P. Sinnappurajar, T. Templeton, S. Wen O0492Identification of conserved detrimental host immune response predicts severity of bacterial and viral infections P. Khatri* (Palo Alto, United States), M. Freedman, H. Zheng, A. Rao, L. Murphy Jones, D. Dermadi, B. Solomon, L. Kalesinskas O0493Genome wide association study reveals pathogen genomic factors associated with patient outcome in Escherichia coli bloodstream infections S. Lipworth* (Oxford, United Kingdom), K. Vihta, K. Chau, L. Barker, S. George, J. Kavanagh, T. Davies, A. Vaughan, M. Andersson, K. Jeffery, S. Oakley, M. Morgan, S. Hopkins, T. Peto, D. Crook, A.S. Walker, N. Stoesser O0494A robust whole blood mRNA combination identify septic patients at high risk of mortality at day-28 after ICU admission L. Kreitmann* (Lyon, France), M.A. Cazalis, G. Monneret, F. Conti, A. Pachot, K. Brengel-Pesce, J.F. Llitjos O0495A novel 29-mRNA host response test to predict bacterial infections in the emergency department K. Tong-Minh* (Rotterdam, Netherlands), O. Liesenfeld, Y. Van Der Does O0496Developing a sepsis clinical response score to predict mortality in neonates hospitalised in low- and middle-income settings: the NeoSep Recovery Score W. Stöhr* (London, United Kingdom) O0497Early diagnosis of sepsis using novel biomarkers fibroblast growth factor 21 (FGF21) & neutrophil granularity intensity (NEUT-GI) A. Ravindra* (Jodhpur, India), V. Jha, M.K. Garg, D. Kumar, G.K. Bohra, D.S. Meena, N. Midha, S. Khichar, N. Santhanam, A.H. Purohit, P. Purohit, A. Rohila O0498Evaluation of a rapid cellular host response test for risk of development of sepsis in various suspected infection patients in the emergency department (ED) H. O’Neal* (Baton Rouge, United States), R. Sheybani, T. Caffery, H. Tse, A. Shah, C. Thomas O0499BIRC6 modifies risk of invasive bacterial infection in Kenyan children J. Gilchrist* (Oxford, United Kingdom), S. Kariuki, J. Watson, G. Band, S. Uyoga, C. Ndila, N. Mturi, S. Mwarumba, M. Mosobo, S. Mohammed, K. Rockett, A. Mentzer, D. Kwiatkowski, A. Hill, J. Scott, T. Williams O0500A trans-ancestry genomics-based approach to study the interplay between the immune system, pathogen virulence, and HLA type, ancestry and sepsis outcome S. Mangul* (Topanga, United States) Sunday, 24 April 2022Programme Committee Natacha Couto, Bath, United Kingdom, Lauren Cowley, Bath, United Kingdom, Edward Feil, Bath, United Kingdom, Benjamin Howden, Melbourne, Australia Kristin Hegstad, Tromsø, Norway, Ângela Novais, Porto, Portugal Sandra Reuter, Freiburg, Germany, Samuel Sheppard, Bath, United Kingdom, Guido Werner, Wernigerode, Germany, Contact: conferences@escmid.org Find more information and registration information on our website www.escmid.org/research_projects/escmid_conferences/immem_xiii “Establishing whole genome sequencing at the core of epidemiological surveillance” Platforms for genome-based typing and epidemiology Incorporating new data types for real-time, genome-based surveillance Genome-based nomenclature Zoonosis, intensive food production and One Health Genomic epidemiology of neglected pathogens Genomic sequencing in LMIC The promise of long read sequencing Plasmid biology 2.0 Lessons learned from COVID-19 Metagenomics and Public Health 13th International Meeting on Microbial Epidemiological Markers (IMMEM XIII) Bath, United Kingdom 14–17 September 2022 Register now!SCIENTIFIC PROGRAMME102 Sunday, 24 April 2022 OS121 16:15 - 18:15 Hall G 2-Hour Oral Session Genomic epidemiology of nosocomial infections ChairsPatrick Harris (Herston, Australia) Guido Werner (Wernigerode, Germany) O0501Hypervariable-Locus Melting Typing (HLMT) protocol for the simultaneous detection and typing of Serratiamarcescens: a rapid and cost effective tool to limit outbreaks in neonatal intensive care units (NICUs) F. Comandatore* (Milan, Italy), A. Alvaro, A. Piazza, M. Perini, A.R. Pasala, S. Papaleo, S. Panelli, T. Nardi, S.G. Rimoldi, C. Mauri, M. Corbella, A. Cavallero, C. Farina, G.V. Zuccotti O0502Whole genome sequencing reveals two simultaneous outbreaks involving VIM-2 positive ST111 and blaOXA-74 positive ST235 Pseudomonas aeruginosa A. Rath* (Regensburg, Germany), S. Blaas, M. Pfeifer, B. Kieninger, J. Fritsch, A. Caplunik- Pratsch, W. Schneider-Brachert, T. Holzmann O0503Dissemination of a mosaic transposon carrying 14 different antimicrobial resistance genes driven by a polyclonal outbreak in two hospitals L. Van Alphen* (Maastricht, Netherlands), C. Jamin, E. Heddema, W. Van Der Zwet, C. Hoebe, P. Savelkoul O0504Comprehensive genomic investigation into in- host evolution of vancomycin resistant Enterococcus faecium over 3.5 years H. Seth-Smith* (Basel, Switzerland), A. Durovic, T. Roloff, M. Meola, C. Casanova, S. Tschudin-Sutter, A. Egli O0505Simulation of a real-time transmission surveillance using Fourier-transform infrared spectroscopy and whole genome sequencing for strain typing S. Wolf* (Tübingen, Germany), E. Barth-Jakschic, B. Bader, S. Peter, J. Liese O0506Transmission routes of Pseudomonas aeruginosa in an intensive care unit identified by WGS C. Couchoud* (Besançon, France), X. Bertrand, B. Valot, D. Hocquet O0507Genomic epidemiology and characterisation of methicillin-resistantStaphylococcus aureus from bloodstream infections in China Y. Jin* (Hangzhou, China), W. Zhou, Y. Xiao O0508Vancomycin-resistant Enterococcus faecium isolates attributed to clusters among hospitalised patients across different hospitals and hospital trusts in Berlin, Germany: results from routine outbreak and transmission analyses F. Maechler* (Berlin, Germany), A. Weber, P. Gastmeier, M. Behnke, A. Kola O0509Routes of transmission of VIM-positive Pseudomonas aeruginosain the adult intensive care unit: an analysis of 9 years of surveillance at a university hospital using a mathematical model A. Büchler* (Rotterdam, Netherlands), T.M. Pham, A.F. Voor In ‘h Holt, J.A. Severin, M.C.J. Bootsma, D. Gommers, M.E. Kretzschmar, M.C. Vos O0510Clinical implementation of routine whole genome sequencing for hospital infection control of multidrug-resistant pathogens B. Forde* (Brisbane, Australia), P. Harris, A. Jennison, K. Hajkowicz, G. Playford, J. Clark, S. Beatson, D. Paterson OS122 16:15 - 18:15 Hall H 2-Hour Oral Session AMR Acinetobacter, Pseudomonas and Salmonella: what is new? ChairsAlvaro Pascual Hernandez (Seville, Spain) Fusun Can (Istanbul, Turkey) O0511Origin, phylogeny, and transmission of the epidemic clone ST208 of carbapenem-resistant Acinetobacter baumannii on a global scale Y. Gao* (Beijing, China), H. Li, H. Chen, J. Zhang, R. Wang, Z. Wang, H. Wang O0512Trends of carbapenem-resistantAcinetobacter baumannii and carbapenem-resistant Pseudomonas aeruginosa in Spain, 2012-21 Á. Asensio Vegas* (Madrid, Spain), M. Cantero Caballero, L.M. Parra Ramírez, A. Vallejo Plaza, R.M. Orti Bordas, I. Salcedo Leal O0513The strategic typhoid alliance across Africa and Asia (STRATAA): genetic epidemiology of typhoidal Salmonella in Blantyre Malawi, Kathmandu Nepal and Dhaka Bangladesh Z. Dyson* (London, United Kingdom), P.M. Ashton, J.E. Meiring, S. Duchene, F. Khanam, A.C. Chirambo, C.L. Msefula, H.C. Banda, B.C. Kutambe, A. Karkey, M. Shakya, S. Tonks, C. Dolecek, S.J. Dunstan, J.D. Clemens, V.E. Pitzer, F. Qadri, B. Basnyat, M.A. Gordon, R.S. Heyderman, G. Dougan, S. Baker, A.J. Pollard, K.E. Holt O0514Antimicrobial resistance and genomic characterisation ofAcinetobacter baumannii andPseudomonas aeruginosaclinical isolates from a nationally representative survey in Saudi Arabia M. Doumith* (Riyadh, Saudi Arabia), R. Bawazeer, S. Alhassinah, A. Alswaji, M. Alzayer, E. Alrashidi, A. Alshahrani, L. Okdah, S. Aljohani, H. Balkhy, M. Alghoribi O0515Molecular characterisation of carbapenem non-susceptible strains of Acinetobacter baumannii and Pseudomonas aeruginosa isolated from a hospital in southern Lima F. Guibert* (Lima, Peru), J. Choque-Matos, K. Espinoza, K. Ocampo, C. Valera, M.J. Pons, J. RuizFINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 2023103 Sunday, 24 April 2022 O0516Characterisation of extensively and pan-drug resistant Acinetobacter baumannii clinical isolates obtained from private and public hospitals in South Africa C. Buys* (Pretoria, South Africa), J. Pitout, K.A. Strydom, C. Kingsburgh, B. Skosana, M. Kock O0517Characterisation of Acinetobacter baumannii- calcoaceticus complex (ABC) pathogens isolated at baseline from patients enrolled in the ATTACK phase III trial A. Miller* (Waltham, United States), S. Mcleod, D. Chabas, G. Poirier, D. Altarac O0518Carbapenemase producing Salmonella from non- human sources in Germany: an update J. Fischer* (Berlin, Germany), A. Bloch, E. Junker, G. Raatz, M. Grobbel, A. Irrgang, C. Deneke, I. Szabo O0519Large-scale analysis of carbapenem-resistant Acinetobacter baumannii reveals patterns of dissemination of ST clades associated with antibiotic resistance M.N. Lurie-Weinberger* (Tel Aviv, Israel), S. Frenk, E. Temkin, A. Keren-Paz, R. Rov, N. Rakovitsky, L. Wullfhart, A. Nutman, M. Paul, G.L. Daikos, E. Durante-Mangoni, D. Yahav, A. Skiada, L. Leibovici, Y. Carmeli O0520Genomic analysis of Salmonella entericaserovar Kentucky ST198 strains isolated over 10 years from clinical cases in Switzerland M. Biggel* (Zurich, Switzerland), J. Horlborg, M. Nüesch-Inderbinen, R. Stephan OS123 16:15 - 18:15 Hall K 2-Hour Oral Session What’s fast, new and relevant in infectious disease diagnostics? ChairsTruls Michael Leegaard (Lørenskog, Norway) Carmen Munoz-Almagro (Barcelona, Spain) O0521Improvement of pre-analytical workflow in a clinical laboratory using lean principles combined with lab automation: impact of the WASP® integration in Hospital General Universitario de Albacete, Spain V. González* (Madrid, Spain), E. Escribano, J. Lozano, J. Parra, A. Garcia, P. Martin, N. Salas, S. Sierra, C. Sainz De Baranda O0522Comparison of conventional culture with T2MR technology for microbial pathogen detection in non-blood specimens collected from paediatric patients M. Agosta* (Rome, Italy), L. Mancinelli, B. Lucignano, M. Onori, S. Al Bitar Nehme, G. Mattana, M. Argentieri, L. Pansani, A. Sisto, A. Santisi, F. Tortora, T. Fragasso, C.F. Perno, P. Bernaschi O0523Comparison of the APAS Independence Automated Plate Reader System with manual Standard-of-Care for processing urine culture specimens D. Pride* (La Jolla, United States), P. Kuo, M. Chiu, P. Ramos, R. Barba O0524Fast lipid analysis technique (FLAT) a rapid, direct from urine diagnostic assay for identification of Gram-negative pathogens R. Ernst* (Baltimore, United States), H. Yang, R. Smith, A. Joshi, D. Goodlett, J. Jennifer O0525Evaluation of a prototype molecular assay to differentiate bacterial versus viral infections from whole blood based on host gene expression M. Faron* (Milwaukee, United States), B. Mesich, A. Cruz, E. Wallace, F. Strouts, D. Persing O0526In vitro pathogen differentiation by mass spectrometry based detection of C-terminal alpha-1-antitrypsin peptides F. Scherr* (Jena, Germany), L. Kasper, F.DEP Hoffmann, S. Neugebauer, B. Hube, L. Tuchscherr, F. Von Eggeling, M. Kiehntopf O0527Electrochemical monitoring of metabolites for detection and label-free identification of microorganisms: towards a smart blood-culture bottle T. Cohu* (Saint-Martin-D’hères, France), P.R. Marcoux, M. Gougis, P. Mailley O0528Clinical evaluation of a new selective medium for non-tuberculous mycobacteria: a prospective multi-centre study J. Esteban* (Madrid, Spain), A. Broncano-Lavado, L. Barrado-Blanco, J. Cacho-Calvo, D. Domingo, J. Garcia-Martinez, S. Hernandez, P. Lopez-Roa, R. Millan-Perez, E. Perez-Cecilia, M.J. Ruiz-Serrano, S. Salso-Ortiz, M. Simon-Sacristan, M. Tato-Diez, C. Toro-Rueda, J.F. Valverde-Canovas O0529Application of MALDI-TOF MS and machine learning for differentiation between the subspecies from Mycobacterium abscessus complex D. Rodriguez-Temporal* (Madrid, Spain), L. Herrera, M.J. Ruiz-Serrano, P. Muñoz, B. Rodríguez-Sánchez O0530Impact of routine molecular point-of-care testing for respiratory pathogens in critically unwell patients with pneumonia: a pragmatic, open- label, randomised controlled trial S. Poole* (Southampton, United Kingdom), A.R. Tanner, V.V. Naidu, F. Borca, H.T.T. Phan, K. Saeed, M.P.W. Grocott, A. Dushianthan, N.J. Brendish, H.E. Moyses, T.W. Clark VW124 16:15 - 17:15 Arena 2 Virtual Walk Through Standardised methods for antimicrobial susceptibility testing ModeratorHelena Zemlickova (Prague, Czech Republic) ReviewerLaurent Dortet (Le Kremlin-Bicêtre, France)SCIENTIFIC PROGRAMME104 Scientific Programme Monday, 25 April 2022 ID ME12507:15 - 08:15Hall C Meet-the-Expert ESCMID & IDSA treatment guidelines for MDR Gram-negative bacterial infections M053107:15Mical Paul (Haifa, Israel) M053207:45Pranita Tamma (Baltimore, United States) ID ME12607:15 - 08:15Hall G Meet-the-Expert Reconciling sepsis initiatives and antimicrobial stewardship programmes M053307:15Jeroen Schouten (Nijmegen, Netherlands) M053407:45Karin Thursky (Carlton, Australia) CM ME12707:15 - 08:15Hall H Meet-the-Expert Hepatitis D Virus: the neglected viral hepatitis M053507:15Cihan Yurdaydin (Ankara, Turkey) M053607:45Ivana Carey (London, United Kingdom) Co-organised with: ESCMID Study Group for Viral Hepatitis (ESGVH), European Society of Virology (ESV) ID ME12807:15 - 08:15Hall I Meet-the-Expert How I treat infections in patients awaiting solid organ transplantation M053707:15Margaret Hannan (Dublin, Ireland) M053807:45Maxime Mallet (Paris, France) CM ME12907:15 - 08:15Hall K Meet-the-Expert Driving the response to EIDs in LMICs with genomics and bioinformatics M053907:15Alan Christoffels (Cape Town, South Africa) M054007:45Christian Happi (Ede, Nigeria) CM ME13007:15 - 08:15Hall N Meet-the-Expert Implementing PK/PD and TDM of anti-infectives in clinical practice M054107:15Sophie Stocker (Camperdown, Australia) M054207:45Federico Pea (Bologna, Italy) Co-organised with: ESCMID PK/PD of Anti- Infectives Study Group (EPASG) IC ME13107:15 - 08:15Hall P Meet-the-Expert How to do infection control, season 2: construction and renovation M054307:15Birgitta Lytsy (Uppsala, Sweden) M054407:45Elisabeth Presterl (Vienna, Austria) Co-organised with: ESCMID Study Group for Nosocomial Infections (ESGNI) CM SY13208:30 - 10:30Hall B Symposium Long-read sequencing: from benchtop to bedside ChairsÂngela Novais (Porto, Portugal) Alex Friedrich (Münster, Germany) S054508:30Characterising pathogens in respiratory samples using rapid metagenomic sequencing Themoula Charalampous (London, United Kingdom) S054609:00Using metagenomics to trace antimicrobial resistance and pathogen along the food chain Thi Thuy Do (Celbridge, Ireland) S054709:30Current state-of-the art in viral diagnostic metagenomics Jutte De Vries (Leiden, Netherlands) S054810:00Quality assessement for clinical shotgun metagenomics Christophe Rodriguez (Creteil, France) Co-organised with: ESCMID Study Group for Epidemiological Markers (ESGEM), ESCMID Study Group for Genomic and Molecular Diagnostics (ESGMD) Presentations in light grey were not registered at the time of publishing.FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 2023105 ID SY13308:30 - 10:30Hall C Symposium Severe skin and soft tissue infection ChairsJodi Lindsay (London, United Kingdom) Matthias Zaccarin (Brabrand, Denmark) S054908:30Pathology of toxins Francois Vandenesch (Lyon, France) S055009:00Antimicrobial therapy Kristina Öbrink-Hansen (Herning, Denmark) S055109:30Surgical evaluation and intervention Christian Eckmann (Hannover, Germany) S055210:00Prospects for immunological interventions: IVIG- therapy Anna Norrby-Teglund (Stockholm, Sweden) Co-organised with: ESCMID Study Group for Staphylococci and Staphylococcal Diseases (ESGS), ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis (ESGBIES), ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) PH SY13408:30 - 10:30Hall E Symposium Past, present and future of pandemics: preparedness and first defense ChairsRobert Leo Skov (Copenhagen, Denmark) Ines Steffens (Solna, Sweden) S055308:30Influenza and the COVID-19 pandemic Nicola Petrosillo (Rome, Italy) S055409:00Viral poliomyelitis: acute flaccid paralysis Nicholas Grassly (London, United Kingdom) S055509:30Ebola and other haemorrhagic fevers Eskild Petersen (Aabyhoj, Denmark) S055610:00What we learnt from COVID-19 for Crimean-Congo haemorrhagic fever Önder Ergönül (Istanbul, Turkey) Co-organised with: ESCMID Study Group for Public Health Microbiology (ESGPHM) ID SY13508:30 - 10:30Hall G Symposium HIV and the reservoir: what is new? ChairsLinos Vandekerckhove (Ghent, Belgium) Annelies Verbon (Utrecht, Netherlands) S055708:30Exploring HIV cure in a resource-limited setting Thumbi Ndung’u (Durban, South Africa) S055809:00New ways to manipulate the reservoir Tokameh Mahmoudi (Rotterdam, Netherlands) S055909:30New immunological insights for destroying the reservoir Marta Massanella Luna (Madrid, Spain) S056010:00What is new in clinical trials? Thomas A. Rasmussen (Aarhus, Denmark) ID SY13608:30 - 10:30Hall J Symposium ESCMID Guidelines for the treatment of infections caused by multidrug-resistant Gram-negatives: a case-based approach ChairsJesús Rodríguez-Baño (Seville, Spain) George L. Daikos (Athens, Greece) S056108:30Cases of cephalosporin-resistant Enterobacterales Thomas Tängdén (Uppsala, Sweden) S056209:00Cases of carbapenem-resistant Enterobacterales Pilar Retamar Gentil (Seville, Spain) S056309:30Cases of multidrug-resistant P. aeruginosa Robert A. Bonomo (Cleveland, United States) S056410:00Cases of multidrug-resistant A. baumannii Elena Carrara (Verona, Italy) IC EW13708:30 - 10:30Hall F Educational Workshop Infectious biofilm in the healthcare environment ChairsCraig Williams (Lancaster, United Kingdom) Elisabeth Presterl (Vienna, Austria) W056508:30Endoscope contamination: why does this happen and how can it be detected? Michelle Alfa (Winnipeg, Canada) W056609:00Water-associated biofilms in the healthcare environment Richard Betham (Scott Creek, Australia) W056710:00Environmental reservoirs of infectious biofilm Karen Vickery (Sydney, Australia) Co-organised with: ESCMID Study Group for Biofilms (ESGB), ESCMID Study Group for Nosocomial Infections (ESGNI) Monday, 25 April 2022SCIENTIFIC PROGRAMME106 OS13808:30 - 10:30Hall D 2-Hour Oral Session Attractive tools aiding the diagnosis of fungal infections ChairsJesus Guinea (Madrid, Spain) Michaela Lackner (Innsbruck, Austria) O0568Respiratory mycobiome in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients A. Shajiei* (Groningen, Netherlands), L. Lui, J. Seinen, W. Dieperink, J.M. Van Dijl, H. Harmsen O0569On the verge of a new typing tool for outbreak analysis: Fourier transform infrared (FT-IR) spectroscopy based typing of azole-resistant bloodstream infection Candida parapsilosis isolates E. De Carolis* (Rome, Italy), B. Falasca, C. Martini, B. Posteraro, M. Sanguinetti O0570Usefulness of 18F-FDG PET-CT for the management of invasive fungal infections A. Fernandez Cruz* (Madrid, Spain), I. Gutiérrez- Martín, S. García-Prieto, K. Velásquez, J. Calderón- Parra, M. Calvo, A. Ramos-Martínez, E. Múñez- Rubio, A. Callejas-Díaz, A. Díaz De Santiago, S. De La Fuente-Moral, I. Sánchez-Romero, B. Rodríguez-Alfonso, A. Fernández-Cruz O0571Predictive model combining serial (1,3)- β -d- glucan assay, risk factors and clinical signs for the diagnosis of invasive candidiasis in ICU patients: a prospective study F. Olearo* (Hamburg, Germany), B. Abdennadher, D. Wichmann, S. Kluge, A. Hot, M. Aepfelbacher, H. Rohde, M. Christner O0572Comparison of four diagnostic criteria for invasive pulmonary aspergillosis: a diagnostic accuracy study in critically ill patients M. Schroeder* (Hamburg, Germany), M. Giese, C. Wijaya, S. Winterland, A. Nuechtern, J. Grensemann, H. Matthews, D. Wichmann, H. Rohde, M. Christner, A.K. Ozga, S. Steurer, A. Heinemann, M. Simon, M. Fischer, S. Kluge O0573Active screening of CAPA in ICU with serum beta- glucan and endotracheal aspirates galactomannan and fungal culture P. Pavone* (Reggio Emilia, Italy), G. Russello, G. Salati, P. Salsi, L. Spaggiari, R. Corsini, L. Vizzini, P. Nardini, V. Menozzi, A. Spadoni, F.G. Piccioni, E. Carretto, M. Massari O0574A DNA-sequencing workflow for mucormycosis diagnosis and species identification on native clinical samples S. Imbert* (Bordeaux, France), E. Pfister, B. Tauzin, M. Hernandez-Grande, M.E. Lafon, L. Delhaes O0575Comparison the efficacy of semi-nested PCR with PCR/HRM in detection/identification of mucormycosis from fresh clinical specimens using Mucorales specific primers K. Ahmadikia* (Tehran, Iran, Islamic Republic of), S. Rezaie, S.J. Hashemi, R. Daie Ghazvini, S. Khodavaisy, H. Mirhendi, R. Mohammadi, E. Roilides O0576The clinical sensitivity of 1,3-beta-D-glucan in candidaemia patients Y.W. Lee* (Seoul, Korea, Republic of), S.Y. Lim, H.J. Park, H. Sung, M.N. Kim, S. Bae, J. Jung, M.J. Kim, S.H. Kim, S.H. Choi, Y.S. Kim, Y.P. Chong O0577Molecular characterisation and phylogenetic analysis of Aspergillus Terrei in a tertiary hospital in Spain during 2018-2020 A.T.B. Tristancho-Baró* (Zaragoza, Spain), C.L.F. Lass-Flörl, N.L. Lackner, C.L. López-Gómez, O.A. Algara-Robles, A.R.L. Rezusta-López OS13908:30 - 10:30Hall H 2-Hour Oral Session Epidemic dynamics and transmission during the COVID-19 pandemic ChairsEmine Alp Mese (Ankara, Turkey) Evangelos Giamarellos-Bourboulis (Athens, Greece) O0577AMulti-centre evaluation of the COVID-19 pandemic’s impact on antimicrobial resistance across United States hospitals K.A. Bauer* (Kenilworth, United States), L.A. Puzniak, K.C. Yu, K.P. Klinker, J. Watts, P.A. Moise, L. Finelli, V. Gupta O0578Risk of SARS-CoV-2 infection among members of a fitness centre chain in Stockholm, Sweden 2020: is going to the gym risky? A. Kongelf* (Solna, Sweden), A. Kongef, J. Collin, M. Axelsson, L. Van Leest, A. Wallensten, M. Rehn O0579Dancing with COVID-19: rapid spread of the Delta variant in bars and nightclubs after relaxation of infection control measures in the Netherlands J. Dingemans* (Maastricht, Netherlands), K. Gorgels, B. Van Der Veer, V. Hackert, C. Den Heijer, L. Van Alphen, C. Hoebe, P. Savelkoul O0580Phylodynamics of SARS-CoV-2 transmission in France, 2020 B. Visseaux* (Paris, France), R. Coppée, F. Blanquart, V. Leducq, K. Zafilaza, A.M. Franco- Rusti, L. Daniel, C. Charpentier, A. Jary, V. Calvez, D. Descamps, A.G. Marcellin, A. Bridier-Nahmias O0581SURCOEFF: survey quantification and NGS genotyping of SARS-CoV-2 in effluents from wastewater plants, town districts and nursing homes, a story of waves S. Alain* (Limoges, France), M. Gaschet, M. Gomez-Mayeras, V. Tilloy, E. Guérin, E. Barouillet, L. Alifat, J. Jouan, G. Boissière, M. Courant, O. Merle, B. Bertin, P. Dehail, H. Habarou, F. Huré, M.C. Ploy, E.R. Lombertie, M. Crouzoulon, C. Dagot O0582Assessment of maternal and neonatal SARS- CoV-2 antibodies in Northern Italy in pre- vaccination era L. Gabrielli* (Bologna, Italy), E.C. Borgatti, C. Marsico, M.G. Capretti, G. Simonazzi, S. Venturoli, M. Lenzi, F. Sandri, T. Lazzarotto Monday, 25 April 2022FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 2023107 O0583Genomic investigation of the spatio-temporal SARS-CoV-2 spread during the first pandemic wave in the canton of Vaud, Switzerland Y. Choi* (Lausanne, Switzerland), D. Jacot, A. Ladoy, D. Deridder, T. Pillonel, S. Vuilleumier, S. Joost, C. Bertelli, G. Greub O0584Leveraging of the semi-quantification of SARS- CoV-2 RT-PCR results to forecast epidemic trends N. Yin* (Brussels, Belgium), S. Van Den Wijngaert, L. Mekkaoui, C. Michel, G. Zorzi, D. Van Cauteren, M. Hallin, D. Martiny, O. Vandenberg O0585Airborne transmission of SARS-CoV-2 lineage B.1.617.2 (Delta variant) within a tightly monitored isolation facility A. Fox-Lewis* (Auckland, New Zealand), F. Williamson, J. Harrower, X. Ren, G.J.B. Sonder, A. Mcneill, J. De Ligt, J.L. Geoghegan O0586Trends in SARS-CoV-2 seroprevalence in Massachusetts estimated from newborn screening specimens K. Ma* (Boston, United States), J. Hale, Y. Grad, G. Alter, K. Luzuriaga, R. Eaton, S. Fischinger, D. Kaur, R. Brody, S. Siddiqui, D. Leach, C. Brown, R.M. Klevens, L. Madoff, A. Comeau OS14008:30 - 10:30Hall I 2-Hour Oral Session Clinical considerations for tropical disease management ChairsZeno Bisoffi (Negrar, Italy) Maria João Lopes (Amadora, Portugal) O0587Associated risk of Blastocystisinfection in colorectal cancer L. Labania* (Al Ain, United Arab Emirates), S. Zoughbor, A. Hassan, H. Alktifan, M. Alktifan, S. Alnuaimi, S. Ajab, M. Olanda, Z. Al Rasbi O0588Correlations of serological routine markers with PET-CTI tracer uptake and lesion size, and the possible impact for future follow-up strategies in alveolar echinococcosis L. Peters* (Ulm, Germany), J.F. Hotz, S. Kapp- Schwörer, N. Eberhardt, A. Essig, B. Grüner, J.B. Hagemann O0589Interferon gamma release assay (IGRA) in the diagnosis of congenital toxoplasmosis A. Vola* (Pavia, Italy), G. Ferrari, G. Cornaro, A. Bonetti, V. Meroni O0590Implementation of C-reactive protein point- of-care testing to improve antibiotic targeting in respiratory illness in Vietnamese primary care (ICAT): a cluster-randomised controlled trial T.T.N. Do* (Hanoi, Vietnam), T.V.D. Vu, R.C. Greer, S. Dittrich, M. Vandendorpe, N.T. Pham, T.D.N. Ta, H.T. Cao, T.V. Khuong, T.B.T. Le, T.H. Duong, T.H. Nguyen, N.T.H. Cai, T.Q.T. Nguyen, S.T. Trinh, H.R. Van Doorn, Y. Lubell, S.O. Lewycka O0591Field experiences with handheld diagnostic devices to triage children under five presenting with severe febrile illness in a district hospital in DR Congo B. Tack* (Antwerp, Belgium), D. Vita, A. Luyindula, I. Mansosa, T. Nsema, O. Lunguya, J. Jacobs O0592Comparative proteomic analysis revealed differential expression of human plasma proteins between two clinically-different cystic echinococcosis groups and provide insights into their potential prognostic accuracy E. Ben Salah* (Monastir, Tunisia), C. Barrera, W. Sakly, S. Mosbahi, T. Balliau, B. Gottstein, A. Ksia, M. Belguith, H. Babba, L. Millon O0593Microbiologic causes of and outcomes from fever among patients receiving chemotherapy for the treatment of solid tumours in Uganda E.A. Gulleen* (Seattle, United States), S.V. Adams, I. Mbrusha, D. Mubiru, B. Pedun, S. Heysell, M. Keng, W. Phipps, A. Omoding, C.C. Moore O0594Inappropriate prescription of antibiotics among children in the community of three low- and middle-income countries B.T. Huynh* (Paris, France), A. Ardillon, L. Ramblière, A. De Lauzanne, P. Herindrainy, J.B. Diouf, Z.Z. Andrianirina, T. Sok, M. Landau, L. Borand, F. Diene Sarr, M. Vray, J.M. Collard, E. Delarocque-Astagneau, D. Guillemot, E. Kermorvant-Duchemin O0595The bioavailability of albendazole depending on fat intake: is it time to change recommendations? L. Peters* (Ulm, Germany), K. Wolf, S. Burkert, B. Grüner O0596Molecular infectious disease diagnostics for tropical parasitoses in returnees from the tropics in compliance with EU Regulation 2017/746 (“CE- IVD Directive”) H. Frickmann* (Hamburg, Germany) OS14108:30 - 10:30Hall K 2-Hour Oral Session Cutting edge in mycobacterial research ChairsJon S. Friedland (London, United Kingdom) Delia Goletti (Rome, Italy) O0597Platelets regulate monocyte collagenase-driven morbidity in tuberculosis through diverse signalling pathways D.E. Kirwan* (London, United Kingdom), R.H. Gilman, J.S. Friedland O0598Functional genetic variation in PE and PPE genes contributes to diversity in Mycobacterium tuberculosis and potential interactions with the human host P. Gómez González* (London, United Kingdom), P.J. Gómez-González, S. Campino, M. Hibberd, L. Tientcheu, J. Phelan, T. Clark Monday, 25 April 2022SCIENTIFIC PROGRAMME108 O0599Fluoroquinolone resistance in a global compendium of Mycobacterium tuberculosis isolates A. Brankin* (Oxford, United Kingdom), K. Malone, P. Fowler, A.S. Walker O0600A comprehensive evaluation of the diagnostic performance of reported lipoarabinomannan assays on tuberculosis infection: a systematic review and meta-analysis of 159 studies Y. Zhou* (Chengdu, China), M. Lyv, Y. Chen, Y. Wang, Y. Cheng, B. Ying O0601What is the role of rifampicin within the standard regimen for M. avium? A hollow-fibre study J. Raaijmakers* (Nijmegen, Netherlands), J. Schildkraut, J. Van Ingen O0602Molecular epidemiology of Mycobacterium abscessus isolates recovered from German cystic fibrosis patients N. Wetzstein* (Frankfurt, Germany), M. Diricks, T.A. Kohl, T.A. Wichelhaus, S. Andres, L. Pawloski, C. Schwarz, A. Lewin, J. Kehrmann, B. Kahl, K. Dichtl, C. Hügel, O. Eickmeier, C. Smaczny, A. Schmidt, S. Zimmermann, L. Nährlich, S. Hafkemeyer, S. Niemann, F.P. Maurer, M. Hogardt O0603Efficacyand mode of action of a direct inhibitor of Mycobacterium abscessus InhA L. Kremer* (Montpellier, France), M. Alcaraz, F. Roquet-Banères O0604Revised definitions of pre-XDR/XDR-tuberculosis and treatment outcomes in France (2006-2019) Y. Kherabi* (Paris, France), M. Jachym-Frechet, C. Rioux, Y. Yazdanpanah, V. Pourcher, J. Robert, L. Guglielmetti O0605Preclinical assessment of apramycin as a candidate for the treatment of Mycobacterium abscessus infections M. Gysin* (Zurich, Switzerland), D. Verma, K. Haldimann, K. Becker, D. Ordway, S.N. Hobbie O0606Ethambutol and meropenem/clavulanic acid synergy promotes extracellular and intracellular killing of Mycobacterium tuberculosis F. Olivença* (Lisbon, Portugal), D. Pires, C. Silveiro, E. Anes, M.J. Catalão VW14208:30 - 09:30Arena 2 Virtual Walk Through A COVID-19 walk-through ModeratorNeven Papic (Zagreb, Croatia) ReviewerIrina-Cristiana Ianache (Bucharest, Romania) CM KN14311:00 - 12:00Hall A Keynote Scientific interview Advances in clinical antibacterial resistance research Interviewer Leonard Leibovici (Petah-Tiqva, Israel) K060711:00 Evelina Tacconelli (Verona, Italy) Evelina Tacconelli is the Director of the Infectious Diseases Section at Verona University Hospital, Italy, and serves as the Senior Consultant on Antimicrobial Resistance at the Department of Internal Medicine, DZIF Clinical Research Unit at the University of Tübingen, Germany. Previously, she coordinated the WHO priority list of antibiotic resistant bacteria for the research and development of new effective antibiotics as well as the WHO project on limitations of estimates of the burden of antibiotic resistant infections within the GLASS (Global Surveillance of Resistant Severe Infections) project. Prof. Tacconelli is a Chair of the European Committee for Infection Control (EUCIC), WHO and ECDC (European Centre for Disease Prevention and Control) consultant for infection control and antimicrobial stewardship. She currently serves as a coordinator of the Italian working group on optimising antibiotics’ prescriptions for AIFA, the Italian Medicine Agency. She is a chief author of the ESCMID guidelines for the management and control of infections due to MDR-Gram negatives and the EUCIC guidelines for the decolonisation of MDR-gram negatives and surgical prophylaxis in colonised patients. For years she has participated and coordinated the European projects and networks focused on antimicrobial resistance. She is a leader and coordinator of ORCHESTRA - Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic, a research project funded by the European Union’s Horizon 2020 Programme aimingatapplyinganinnovativeapproachtofightagainst COVID-19 and improve the management of future pandemics. Fireplace Session 25 April, 14:30 - 15:30 CM SY14411:00 - 12:00Hall B Symposium Beyond species ID: Innovative uses of MALDI-TOF in the clinical microbiology lab ChairsJacob Moran-Gilad (Be'er Sheva, Israel) Antonella Lupetti (Pisa, Italy) S060811:00MALDI-TOF for AMR detection and outbreak tracking in the hospital setting Lucie Amoureux (Dijon, France) S060911:30Phenotype prediction using MALDI-TOF data and machine learning Adrian Egli (Basel, Switzerland) Monday, 25 April 2022FINAL PROGRAMME – 33RD ECCMID Copenhagen, Denmark 2023109 Monday, 25 April 2022 ID SY14511:00 - 12:00Hall C Symposium Tuberculous meningitis ChairsCamilla Rodrigues (Mumbai, India) Reinout Van Crevel (Nijmegen, Netherlands) S061011:00Diagnosis and treatment of TB meningitis: what’s new? Fiona Cresswell (Kampala, Uganda) S061111:30An update on the management of childhood TBM Ronald Van Toorn (Western Cape, South Africa) Co-organised with: Trainee Association of ESCMID (TAE), European Society for Paediatric Infetious Diseases (ESPID) PH SY14611:00 - 12:00Hall E Symposium Communicating COVID-19: fact and fiction ChairsJoel Mossong (Findel, Luxembourg) Jonas Sivelä (Helsinki, Finland) S061211:00Online activity in 2020-2021: what happened, and who was active? Francesco Gesualdo (Rome, Italy) S061311:30Communicating new vaccines: lessons learnt from listening online Bea Rofagha (Brussels, Belgium) Co-organised with: ESCMID Vaccine Study Group (EVASG) CM SY14711:00 - 12:00Hall H Symposium Using water to monitor circulating pathogens ChairsAna R. Freitas (Porto, Portugal) Ed Feil (Bath, United Kingdom) S061411:00An interplay between antibiotics residues and antibiotic resistance genes in wastewater Katariina Pärnänen (Turku, Finland) S061511:30Sewage surveillance of antibiotic resistance: a complement to traditional clinical surveillance Joakim Larsson (Gothenburg, Sweden) Co-organised with: ESCMID Study Group for Epidemiological Markers (ESGEM), ESCMID Food- and Water-borne Infections Study Group (EFWISG), Portuguese Society of Microbiology (SPM) ID SY14811:00 - 12:00Hall J Symposium Prediction and prognosis of Staphylococcus aureus pneumonia ChairsMarc Stegger (Copenhagen, Denmark) Barbara C. Kahl (Münster, Germany) S061611:00Prognostic factors of severe community- acquired staphylococcal pneumonia Yves Gillet (Lyon, France) S061711:30Host and bacterial factors in the prevalence and outcome of severe S. aureus bacteremia and sepsis in the tropics Steven Tong (Surrey Hills, Australia) Co-organised with: ESCMID Study Group for Staphylococci and Staphylococcal Diseases (ESGS), ESCMID Study Group for Respiratory viruses (ESGREV) CM SY14911:00 - 12:00Hall M Symposium mecC MRSA: epidemiology and evolution ChairsStefan Börjesson (Solna, Sweden) Patricia Poeta (Vila Real, Portugal) S061811:00Natural reservoirs of mecC MRSA Carmen Torres (Logroño, Spain) S061911:30mecC MRSA in hedgehogs predates the antibiotic era Jesper Larsen (Copenhagen, Denmark) ID SY15011:00 - 12:00Hall N Symposium Top papers in mycology ChairsJustin Beardsley (Sydney, Australia) Angela Loyse (London, United Kingdom) S062011:00Advances in treatment and drug susceptibility Nelesh Govender (Johannesburg, South Africa) S062111:30Fungal pathogenesis and its application Mihai Gheorghe Netea (Nijmegen, Netherlands) IC SY15111:00 - 12:00Hall Q Symposium Clostridioides difficile infection: importance of learning from patients experience ChairsBenoit Guery (Lausanne, Switzerland) Marcela Krutova (Prague, Czech Republic) S062211:00Letters from the Home Front: patient experiences of CDI and what they mean for CDI research Jane Freeman (Leeds, United Kingdom)Next >